• Users Online: 14
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Ahead of print Current issue Search Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2020  |  Volume : 18  |  Issue : 1  |  Page : 22-26

Predonation iron and hematological status of whole blood donors in lagos, Nigeria: Impact on blood supply


1 Department of Haematology and Blood Transfusion , College of Medicine, University of Lagos, Lagos, Nigeria
2 Department of Chemical Pathology, College of Medicine, University of Lagos, Lagos, Nigeria
3 Department of Division of Epidemiology and Biostatistics, School of Public Health, University of Witwatersrand, Johannesburg, South Africa

Correspondence Address:
Sarah O John-Olabode
Department of Haematology and Blood Transfusion, College of Medicine, University of Lagos, Lagos State
Nigeria
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/NJGP.NJGP_8_19

Rights and Permissions

Context: Regular blood donations can engender iron depletion and its complications; reducing the prevalence of iron depletion among blood donors is a key strategy for optimizing donors' health. However, the factors impacting on iron deficiency among blood donors are not yet well characterized in our environment. Aim: The aim of this study is to determine predonation iron status and hematological profile among blood donors. Settings and Design: We conducted a comparative cross-sectional study of eligible blood donors at Lagos University Teaching Hospital. Consenting participants were consecutively recruited. Materials and Methods: Sociodemographic data were collected using an interviewer-administered questionnaire. Blood samples for estimation of ferritin, serum iron, total iron-binding capacity, and complete blood count were collected. Statistical Analysis Used: Statistical analysis was conducted using Stata version 14 software. Results: About three-fourths of the participants (n = 234, 74.8%) were first-time donors and one-fourth (n = 79, 25.2%) were frequent donors. Overall, 16 (5.1%) of the blood donors had depleted iron stores. There was a significant difference in the prevalence of iron depletion between first-time and regular donors (P < 0.01). Multivariable analysis showed that the odds of iron deficiency decreased by 58% for every g/dl increase in hemoglobin levels (odds ratio = 0.42, 95% confidence interval: 0.24–0.73, P = 0.002). Smokers had about 14-fold odds of having iron deficiency as compared to nonsmokers. Conclusion: Although current donation strategies to mitigate donation-related iron loss have resulted in a significant decline in the prevalence of iron deficiency in frequent blood donors, we are still a long way from keeping our iron-replete blood donors.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed371    
    Printed43    
    Emailed0    
    PDF Downloaded55    
    Comments [Add]    

Recommend this journal